成员：吴智华

（一）学习及工作经历

2018.9-至今：中南民族大学生命科学学院从事教学科研工作

2014.6-2018.8：华中农业大学生命科学技术学院，博士后

2009.9-2014.5：武汉大学生命科学学院遗传学专业，获理学博士学位

2005.9-2009.6：湖南科技大学生物科学专业，获理学学士学位

（二）其它学术兼职及荣誉

2011年，获武汉大学生命科学学院优秀共产党员称号

2011年，获武汉大学优秀研究生称号和甲等奖学金

2012年，获聘湖北省普通高考评卷员

2012年，获武汉大学研究生学术创新奖二等奖

2014年，担任Scientific Research and Essays期刊审稿人

2018年，湖北省生物信息学会会员

2019年，获华中农业大学优秀博士后表彰奖励

（三）主要研究方向

生物信息学

功能基因组学

系统进化生物学

（四）主持或参与的科研项目

1.主持：中国博士后科学基金面上项目，2015M582235，大豆基因共表达网络的构建及激素 调控基因表达网络研究，5万，2015/10-2017/11

2.参与：国家自然科学基金专项基金/应急项目，31540080，光信号与油菜素甾醇协同控制水稻叶枕发育的细胞和分子机制，2016/1-2016/12

3.参与：国家自然科学基金面上项目，31271310，中国莲基因组遗传图谱的构建和连锁群染 色体定位，2013/1-2016/12

4.参与：“973”项目，2007CB108705，植物育性转换的孟德尔与非孟德尔遗传学机理与应 用，2007/1－2012/12

5.参与：国家自然科学基金重大研究计划，91535104, RLA1及其互作蛋白参与油菜素甾醇信号转导并调控水稻株型的细胞、遗传和分子机制研究，2016/1-2017/12

6.参与：国家自然科学基金面上项目，光调控大豆结瘤的机制研究， 31871227，59万元，2019/1-2022/12

7.参与：国家自然科学基金国际合作项目，31661143024，油菜素甾醇调控植物响应高温和低磷环境胁迫的机制研究，166万元，2017/12-2019/12

8.参与：国家自然科学基金重大研究计划，91317302，油菜素甾醇与其它信号途径协调控制植物器官发育的细胞和分子机制研究，200万元，2014/1-2015/12

 

 

（五）代表性论著

1.Zhihua Wu, Meirong Wang, Siyu Yang, Shengcai Chen, Xu Chen, Chang Liu, Shixiang Wang, Haijiao Wang, Bao Zhang, Hong Liu, Rui Qin, and Xuelu Wang*. A global coexpression network of soybean genes gives insight into the evolution of nodulation in non-legumes and legumes. New Phytologist, 2019, 10.1111/nph.15845.

2. Zhihua Wu, Songtao Gui; Zhiwu Quan; Lei Pan; Shuzhen Wang; Weidong Ke, Dequan Liang; Yi Ding (*) A precise chloroplast genome of Nelumbo nucifera (Nelumbonaceae) evaluated with Sanger, Illumina MiSeq, and PacBio RS II , sequencing platforms: insight into the plastid evolution of basal eudicots. BMC Plant Biology 2014 14(289): 1-14.

3. Zhihua Wu, Songtao Gui; Shuzhen Wang; Yi Ding(*) Molecular evolution and functional characterisation of an ancient phenylalanine ammonia-lyase gene (NnPAL1) from Nelumbo nucifera: novel insight into the evolution of the PAL family in angiosperms. BMC Evolutionary Biology 2014 14(100): 1-14.

4. Zhihua Wu, Shuzhen Wang; Jihong Hu; Feng Li; Weidong Ke; Yi Ding(*) Development and characterization of microsatellite markers for Sagittaria trifolia var. sinensis (Alismataceae). American Journal of Botany 2011 98(2):36-38.

5. Songtao Gui，Zhihua Wu (#)， Hongyuan Zhang，Yinzhen Zheng，Zhixuan (#) , Zhu，Dequan Liang，Yi Ding (*) The mitochondrial genome map of Nelumbo nucifera reveals ancient evolutionary features. Scientific Reports 2016 6: 1-11.

6. Songtao Gui, Jing Peng, Xiaolei Wang, Zhihua Wu, Rui Cao, Jérôme Salse, Hongyuan Zhang, Zhixuan Zhu, Qiuju Xia, Zhiwu Quan, Liping Shu, Wedong Ke and Yi Ding* Improving Nelumbo nucifera genome assemblies using high-resolution genetic maps and BioNano genome mapping reveals ancient chromosome rearrangements. Plant Journal 2018, 94(4):721-734.

7. Tao Wang, Chengxiang Li, Zhihua Wu, Yancui Jia, Hong Wang, Shiyong Sun, Chuanzao Mao, Xuelu Wang*. Abscisic Acid Regulates Auxin Homeostasis in Rice Root Tips to Promote Root Hair Elongation, Frontiers in Plant Sciences, 2017.6.8, 8(1121): 1~18.

8. Lei Pan, Nian Wang, Zhihua Wu, Rui Guo, Xiaolu Yu, Yu Zheng, Qiuju Xia, Songtao Gui, Chanyou Chen*. A High Density Genetic Map Derived from RAD Sequencing and Its Application in QTL Analysis of Yield-Related Traits in Vigna unguiculata, Frontiers in Plant Science, 2017.9.7, 8(1544): 1~13.

9. Shenglong Qiao#, Shiyong Sun#, Linlin Wang, Zhihua Wu, Chengxiang Li, Xiaoming Li, Tao Wang, Linna Leng, Weisheng Tian, Tiegang Lu, and Xuelu Wang*. The RLA1/SMOS1 Transcription Factor Functions with OsBZR1 to Regulate Brassinosteroid Signaling and Rice Architecture. Plant Cell 2016, 29(2):292-309.

10. Dongxu Wang, Cangjing Yang, Haijiao Wang, Zhihua Wu, Jianjun Jiang, Jingjing Liu, Zhuona He, Fang Chang, Hong Ma, Xuelu Wang*. BKI1 Regulates Plant Architecture through Coordinated Inhibition of the Brassinosteroid and ERECTA Signaling Pathways in Arabidopsis. Molecular plant, 2016, 10(2):297-308.

11. Zhixuan Zhu, Songtao Gui, Jing Jin, Rong Yi, Zhihua Wu, Qian Qian, Yi Ding*. The NnCenH3 Protein and Centromeric DNA Sequence Profiles of Sacred Lotus (Nelumbo nucifera Gaertn.) Reveal the DNA Structures and Dynamics of Centromeres in Basal Eudicots. Plant Journal, 2016, 87(6):568-82.

12. Jianjun Jiang, Tao Wang, Zhihua Wu, Jie Wang, Chi Zhang, Haijiao Wang, Zhi-Xin Wang, Xuelu Wang*. The Intrinsically Disordered Protein BKI1 Is Essential for Inhibiting BRI1 Signaling in Plants. Molecular plant, 2015, 8(11):1675–1678.

13. Shuzhen Wang, Yinzhen Zheng, Junjie Yan, Zhixuan Zhu, Zhihua Wu and Yi Ding*. Alpha-momorcharin: A Ribosome-Inactivating Protein from Momordica charantia, Possessing DNA Cleavage Properties. Protein & Peptide Letters 2013, 20:1257-1263.

14. Shuzhen Wang, Yubo Zhang, Honggao Liu, Ying He, Junjie Yan, Zhihua Wu, and Yi Ding*. Molecular cloning and functional analysis of a recombinant ribosome-inactivating protein (alpha-Momorcharin) from Momordica charantia. Applied Microbiology and Biotechnology 2012, 96:939–950.

15. Jihong Hu, Lei Pan, Honggao Liu, Shuzhen Wang, Zhihua Wu, Weidong Ke, and Yi Ding*. Comparative analysis of genetic diversity in sacred lotus (Nelumbo nucifera Gaertn.) using AFLP and SSR markers. Molecular Biology Reports 2012, 39:3637–3647.